Annual Review of Political Science

Causal Inference, Agency, and the Problem of Inherent Endogeneity

2025-11-26

Researchers often leverage exogenous variation in an independent variable in order to understand its effects, yet endogenous decision processes are central to many of the real-world phenomena we wish to understand. This review explores whether there are situations in which exogenous and endogenous variation in the same independent variable (e.g., a policy, treatment, or other action) may lead to different outcomes. I begin by laying out a conceptual framework for understanding these inherently endogenous causal processes, identifying three types of mechanisms through which they might arise and discussing their application to a range of empirical phenomena, such as institutional reform, community natural resource governance, and interstate conflict. I then suggest that learning about inherently endogenous causal processes requires researchers to place endogenous decision-making at the center of analysis rather than seeking to abstract away from it. I survey a range of methods (both positivist and nonpositivist) for doing so.

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DOI https://doi.org/10.1146/annurev-polisci-032624-013736