Nature Communications

Copper integrative catalytic pairs with mixed-valence Cu2+-Cu3+ Species for selective alkyne conversion

2025-10-30

Achieving specific orbital activation of C ≡ C by controlling the precise atomic architecture of supported metals is crucial for the selective transformation of alkynes. However, its physical mechanism remains a subject of debate. Herein, we construct a well-defined O-bridged CuN 3 -O-CuN 3 integrative catalytic pairs (Cu ICPs) based on Kirkendall effect. As a result, Cu ICPs with mixed Cu 2+ -Cu 3+ species demonstrate >99% conversion and >550 h stability in acetylene hydrochlorination (simulated industrial reaction conditions), showcasing unparalleled performance in the liquid-phase hydrochlorination of five alkynes as well. A combined experimental and theoretical analyses reveal selective coupling between the d xz / d yz orbitals of Cu ICPs and the σ orbitals of C ≡ C in C 2 H 2 , leading to the formation of highly reactive di- σ -HC = CH intermediate. Additionally, the presence of the bridged-O species promotes HCl dissociation, altering the addition pathway from the classical Eley-Rideal (E-R) mechanism to a Cl•-trigged Langmuir-Hinshelwood (L-H) mechanism, ultimately reducing the intrinsic energy barrier for addition, and breaking the universal standard electrode potential linear scaling relations.

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DOI https://doi.org/10.1038/s41467-025-64639-w