Nature Communications

De novo design of hypercompact transcript degraders by engineering substrate-specific toxins and Cas6-CBS system

• Pin-Ru Chen
• Pei-Pei Qin
• Ya-Nan Wang
• Peng-Fu Liu
• Xin-Yue Zhang
• Tao Qian
• Bang-Ce Ye
• Bin-Cheng Yin

2025-09-26

Full text

DOI https://doi.org/10.1038/s41467-025-63166-y