Science Advances

Discovery of specific rhizosphere bacteria Rhodanobacter involved in KAI2-mediated drought tolerance in Arabidopsis

2026-07-01

The KARRIKIN INSENSITIVE 2 (KAI2) receptor has been reported to contribute to drought tolerance in Arabidopsis . However, the extent to which KAI2’s function in drought tolerance depends on soil microbiota remains unclear. This study demonstrates that the rhizosphere microbiome is indispensable for KAI2-mediated drought tolerance. We isolated specific Rhodanobacter sp. and confirmed its role in enhancing drought tolerance in Arabidopsis . Notably, Rhodanobacter sp. was found to specifically secrete the key isoflavone daidzin. We found that daidzin had a similar function with KAI2 agonist, desmethyl-type germinone, and induced interaction between KAI2 and SUPRESSOR OF MORE AXILLARY GROWTH 2 1. Moreover, the exogenous application of daidzin enhanced drought tolerance by modulating the expression of karrikin response and drought-related genes, in a KAI2-dependent manner. Our findings suggest that the rhizosphere microbiome plays a crucial role in facilitating KAI2-mediated drought tolerance in Arabidopsis , with Rhodanobacter sp. contributing through the secretion of daidzin.

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DOI https://doi.org/10.1126/sciadv.ads2698