Nature

Quadruple pegRNA enables programmable and efficient large genomic insertion

• Ya-jing Shi
• Zi-yi Ding
• Ying Wu
• Zhou He
• Yi-zhou Zhang
• Yu-lu Zhang
• Yu-ming Zhang
• Xiang-rui Huang
• Hao Yin
• Ying Zhang

2026-04-22

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DOI https://doi.org/10.1038/s41586-026-10395-w