Nature Communications

Targeting SMC3 deacetylation synergizes with XPO1 inhibition to reprogram the epigenetic landscape and suppress NPM1-mutated acute myeloid leukemia

• Jianfeng Fu
• Huilin Xu
• Xinying Zhao
• Mengge Gao
• Yonglu Tian
• Yingjun Chang
• Xiaofeng Zheng

2026-06-11

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DOI https://doi.org/10.1038/s41467-026-74343-y