Nature Communications

Trifunctional flavoenzyme-catalyzed asymmetric 4-alkyl-butenolide assembly in avenolide biosynthesis

• Wenrui Li
• Jinlian Zhao
• Weibo Zeng
• Ruifei Zhang
• Lei Yan
• Yuting Fan
• Jiaxin Liu
• Wenzhao Wang
• Gregory L. Challis
• Shanshan Zhou

2026-02-07

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DOI https://doi.org/10.1038/s41467-026-69265-8