Nature Communications

USP1/UAF1 targets polyubiquitinated PCNA with an exo-cleavage mechanism that can temporarily enrich for monoubiquitinated PCNA

• Niels Keijzer
• Jan Sakoltchik
• Kaustav Majumder
• Nina van Lil
• Farid El Oualid
• Alexander Fish
• Titia K. Sixma

2025-07-30

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DOI https://doi.org/10.1038/s41467-025-61768-0